Realization of drug discovery using glycans and lectins
Glycan and lectin research from basic to practical application
Glycans are the most diverse biological code, and cover the surface of all cells, which are the smallest units of life. They are called the “face of the cell” because they change depending on the cell type and state, and they regulate communication between multicellular organisms and between multiple organs. However, glycans have a branched structure, are not template-dependent, and are heterogeneous, making them difficult to analyze, and so they remain an issue in the life sciences, and new breakthroughs are needed.
I am studying the individuality of individual cells that make up a cell population from the perspective of “glycans”, and elucidating the life phenomena that various cells weave together at the molecular level. I am also developing new technologies for sorting individual cells and applying them to medical care. I am conducting research in various fields, including stem cells, cancer, exosomes, and microbial flora, by making full use of recombinant lectins, microarrays, NGS, etc.
We have contributed to the practical application of recombinant lectin libraries, iPS cell markers, lectin arrays, etc. We are currently conducting research with the aim of developing and putting into practical use single-cell glycan sequencing methods and diagnostic and pharmaceutical products for cancer. We have experience of conducting numerous joint research projects with research institutions and companies, so please feel free to contact us. If you are interested in joining our lab, please see JOIN US.
