Itai T, Sugie A, Nitta Y, Maki R, Suzuki T, Shinkai Y, Watanabe Y, Nakano Y, Ichikawa K, Okamoto N, Utsuno Y, Koshimizu E, Fujita A, Hamanaka K, Uchiyama Y, Tsuchida N, Miyake N, Misawa K, Mizuguchi T, Miyatake S, Matsumoto N.
A novel NONO variant that causes developmental delay and cardiac phenotypes
Scientific Reports, 13;975, 2023
Akahoshi Y, Sugai H, Mimura M, Shinkai Y, Kurita R, Shiraki K, Tomita S.
Phase-Separation Propensity of Non-ionic Amino Acids in Peptide-Based Complex Coacervation Systems
Biomacromolecules, 24;2:704–713, 2023
Kuramochi M, Shumiao Z, Takanashi C, Yang Y, Arai T, Shinkai Y, Doi M, Mio K, Tsuda S, Sasaki Y.
A mutation to a fish ice-binding protein synthesized in transgenic Caenorhabditis elegans modulates its cold tolerance
Biochem. Biophys. Res. Commun., 5;628:98-103, 2022
新海陽一、小澤一毅、戸井基道
液液相分離を引き起こすPhe-Glyリピートの持つ可能性
アグリバイオ 2022年8月号「ペプチド工学の新展開」, 2022
Kuramochi M, Dong Y, Yang Y, Arai T, Okada R, Shinkai Y, Doi M, Aoyama K, Sekiguchi H, Mio K, Tsuda S, Sasaki Y.
Dynamic motions of ice-binding proteins in living Caenorhabditis elegans using diffracted X-ray blinking and tracking.
Biochem. Biophys. Rep., 3;29:101224, 2022
2021
Ozawa K, Shinkai Y, Kako K, Fukamizu A, Doi M.
The molecular and neural regulation of ultraviolet light phototaxis and its food-associated learning behavioral plasticity in C. elegans.
Neuroscience Letters, 136384, 2021
Nanaura H, Kawamukai H, Fujiwara A, Uehara T, Aiba U, Nakanishi M, Shiota T, Hibino M, Wiriyasermkul P, Kikuchi S, Nagata R, Matsubayashi M, Shinkai Y, Niwa T, Mannen T, Morikawa N, Iguchi N, Kiriyama T, Morishima K, Inoue R, Sugiyama M, Oda T, Kodera N, Toma-Fukai S, Sato M, Taguchi H, Nagamori S, Shoji O, Ishimori K, Matsumura H, Sugie K, Saio T, Yoshizawa T, Mori E.
C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers.
Nature Communications, 12, 5301, 2021
Mimura M, Tomita S, Sugai H, Shinkai Y, Ishihara S, Kurita R.
Uncharged Components of Single-Stranded DNA Modulate Liquid–Liquid Phase Separation With Cationic Linker Histone H1.
Front. Cell Dev. Biol., 9, 710729, 2021
Shinkai Y, Kuramochi M, Miyafusa T.
New Family Members of FG Repeat Proteins and Their Unexplored Roles During Phase Separation.
Front. Cell Dev. Biol., 9, 708702, 2021
Mimura M, Tomita S, Shinkai Y, Hosokai T, Kumeta H, Saio T, Shiraki K, Kurita R.
Quadruplex Folding Promotes the Condensation of Linker Histones and DNAs via Liquid–Liquid Phase Separation.
J. Am. Chem. Soc., 143, 26, 9849–9857, 2021
Wang X, Shinkai Y, Doi M.
Retrogradely transmitted α-synuclein is taken up by the endophilin-independent endocytosis in the C. elegans neural circuit.
Biochem Biophys Res Commun., 552:176-182, 2021
Doi M, Sato M, Ohmiya Y.
In Vivo Simultaneous Analysis of Gene Expression by Dual-Color Luciferases in Caenorhabditis elegans.
Int. J. Mol. Sci., 22(1), 119, 2021
2020
Suzuki H, Inaba M, Yamada M, Uehara T, Takenouchi T, Mizuno S, Kosaki K, Doi M.
Biallelic loss of OTUD7A causes severe muscular hypotonia, intellectual disability and seizures.
AM J MED GENET A., Dec 31, 2020
Hasegawa T, Takahashi J, Nagasawa S, Doi M, Moriyama A, Iwahashi H.
DNA Strand Break Properties of Protoporphyrin IX by X-Ray Irradiation against Melanoma.
Int J Mol Sci. 26;21(7):2302. 2020.
2019
Ochiishi T, Kaku M, Kiyosue K, Doi M, Urabe T, Hattori N, Shimura H, Ebihara T.
Alzheimer's disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers.
Sci Rep. 22;9(1):17368. 2019.
Akutsu Y, Doi M, Furukawa K, Takagi Y.
Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System.
J Vis Exp. 31;(149). 2019.
Kuramochi M, Takanashi C, Yamauchi A, Doi M, Mio K, Tsuda S, Sasaki YC.
Expression of Ice-Binding Proteins in Caenorhabditis elegans Improves the Survival Rate upon Cold Shock and during Freezing.
Sci Rep. 15;9(1):6246. 2019.
Takagi Y, Nosato H, Doi M, Furukawa K, Sakanashi H.
Development of a motion-based cell-counting system for Trypanosoma parasite using a pattern recognition approach.
Biotechniques. 66(4):179-185. 2019.
Kuramochi M, Doi M.
An Excitatory/Inhibitory Switch From Asymmetric Sensory Neurons Defines Postsynaptic Tuning for a Rapid Response to NaCl in Caenorhabditis elegans.
Front Mol Neurosci. 9;11:484. 2019.
Saito R, Shinkai Y, Doi M.
Intestinal F-box protein regulates quick avoidance behavior of Caenorhabditis elegans to the pathogenic bacterium Pseudomonas aeruginosa.
Genes Cells. 24(3):192-201. 2019.
Takagi Y, Akutsu Y, Doi M, Furukawa K.
Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi.
PLoS Negl Trop Dis. 14;13(1):e0007088. 2019.
2018
Bhargava P, Grover A, Nigam N, Kaul A, Doi M, Ishida Y, Kakuta H, Kaul SC, Terao K, Wadhwa R.
Anticancer activity of the supercritical extract of Brazilian green propolis and its active component, artepillin C: Bioinformatics and experimental analyses of its mechanisms of action.
Int J Oncol. 52(3):925-932.2018.
Shinkai Y., Kuramochi M., Doi M.
A Simple Method for Visualization of Locus-Specific H4K20me1 Modifications in Living Caenorhabditis elegans Single Cells.
G3 (Bethesda)., 2;8(7):2249-2255. 2018.
Shinkai Y., Kuramochi M., Doi M.
Regulation of chromatin states and gene expression during HSN neuronal maturation is mediated by EOR-1/PLZF, MAU-2/cohesin loader, and SWI/SNF complex.
Sci Rep. 21;8(1):7942. 2018.
Shinkai Y., Doi M.
EOR-1 mediates non-cell autonomous regulation of abts-1 gene expression in HSNs.
microPublication Biology. 2018.
▼ 2017以前の発表論文・著書を表示
2017
Kuramochi M. & Doi M.
A Computational Model Based on Multi-Regional Calcium Imaging Represents the Spatio-Temporal Dynamics in a Caenorhabditis elegans Sensory Neuron.
PLoS One，12-1，pp.e0168415, 2017.
2016
Hashimoto M., Doi M., Kurebayashi N., Furukawa K., Hirawake H., Ohmiya Y., Sakurai T., Mita T., Mikoshiba K & Nara T.
Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle.
FEBS Open Bio, 14; 6(12), 1178-1185, 2016.
Chechetka S., Doi M., Pichon BP., Begin-Colin S. & Miyako E.
Photothermal and mechanical stimulation of cells via dualfunctional nanohybrids.
NANOTECHNOLOGY，25;27(47)， 475102-475112, 2016.
Ochiishi T., Doi M., Yamasaki K., Hirose K., Kitamura A., Urabe T., Hattori N., Kinjo M., Ebihara T. & Shimura H.
Development of new fusion proteins for visualizing amyloid-β oligomers in vivo.
Scientific Reports, 16; 6:22712, 2016.
2015
Miyako E., Chechetka S., Doi M., Yuba E. & Kouno K.
In Vivo Remote Control of Reactions in Caenorhabditis elegans by Using Supramolecular Nanohybrids of Carbon Nanotubes and Liposomes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION，54(34)， pp.9903-9906, 2015.
Nakahara Y., Tatsumi Y., Akimoto I., Osaki S., Doi M., and Kimura K
Fluorescent silica nanoparticles modified chemically with terbium complexes as potential bioimaging probes: their fluorescence and colloidal properties in water.
New Journal of Chemistry，39: 1452-1458, 2015.
2013
Doi M., H. Minematsu, Y. Kubota, K. Nishiwaki, and M. Miyamoto
The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.
Development 140: 3435-3444, 2013.
Fukuda N., Doi M. and Honda S.
Yeast one-hybrid gγ recruitment system for identification of protein lipidation motifs.
PLoS One, 26;8(7): e70100, 2013.
2011
Shinkai Y, Yamamoto Y, Fujiwara M, Tabata T, Murayama T, Hirotsu T, Ikeda DD, Tsunozaki M, Iino Y, Bargmann CI, Katsura I, Ishihara T.
Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans.
Journal of Neuroscience, 23;31(8):3007-15. 2011.
2009
Yamashita, M., K. Iwasaki, and M. Doi.
The non-neuronal syntaxin SYN-1 regulates defecation behavior and neural activity in C. elegans through interaction with the Munc13-like protein AEX-1.
Biochemical and Biophysical Research Communications 378: 404-408, 2009.
2008
Tanaka, D., K. Kameyama, H. Okamoto, and M. Doi
The C. elegans Rab escort protein (REP-1) differently regulates each Rab protein function and localization in a tissue-dependent manner.
Genes to Cells 13: 1141-1157, 2008.
Doi, M., and K. Iwasaki
Na+/K+ ATPase regulates the expression and localization of acetylcholine receptors in a pump activity-independent manner.
Molecular and Cellular Neuroscience 38: 548-558, 2008.
2007
Tanaka, D., K. Furusawa, K. Kameyama, H. Okamoto, and M. Doi
Melatonin signaling regulates locomotion behavior and homeostatic states through distinct receptor pathways in Caenorhabditis elegans.
Neuropharmacology 53: 157-168, 2007.
2002
Doi, M., and K. Iwasaki
Regulation of retrograde signaling at neuromuscular junctions by the novel C2 domain protein AEX-1.
Neuron 33: 249-259, 2002.
Yamada, H., T. Sakai, M. Tomaru, M. Doi, M. Matsuda, and Y. Oguma
Search for species-specific mating signal in courtship songs of sympatric sibling species, Drosophila ananassae and D. pallidosa.
Genes Genet System 77: 97-106, 2002.
2001
Doi, M., M. Matsuda, M. Tomaru, H. Matsubayashi, and Y. Oguma
A locus for female discrimination behavior causing sexual isolation in Drosophila.
Proceedings of the National Academic Sciences, U.S.A. 98: 6714-6719, 2001.
2000
Tomaru, M., M. Doi, H. Higuchi, and Y. Oguma
Courtship song recognition in the Drosophila melanogaster complex: heterospecific songs make females receptive in D. melanogaster, but not in D. sechellia.
Evolution 54: 1286-1294, 2000.
1997
Doi, M., T. Nemoto, H. Nakanishi, Y. Kuwahara, and Y. Oguma
Behavioral Response of Males to Major Sex Pheromone Component, (Z,Z)-5,25-Hentriacontadiene, of Drosophila ananassae Females.
Journal of Chemical Ecology 23: 2067-2078, 1997.
1996
Doi, M., M. Tomaru, H. Matsubayashi, K. Yamanoi, and Y. Oguma
Genetic analysis of Drosophila virilis sex pheromone: genetic mapping of the locus producing Z-(11)-pentacosene.
Genetical Research 68: 17-21,1996.
1994
Nemoto, T., M. Doi, K. Oshio, H. Matsubayashi, and Y. Oguma
(Z,Z)-5,27-Tritriacontadiene: Major sex pheromone of Drosophila pallidosa (Diptera; Drosophilidae).
Journal of Chemical Ecology 20: 3029-3037, 1994.
