Intelligence Officer,  Ministry of Home Affairs, North Bock, New Delhi, India: 1995

Junior Research Fellow, UGC-CSIR, RRL, Trivandrum, India: 1995-1997

Senior Research Fellow, UGC-CSIR, RRL, Trivandrum, India, 1998-2000

Postdoctoral Fellow, Joint Research Center for Atom Technology, Tsukuba, Japan: 2000-2002

JSPS Postdoctoral Fellow, AIST, Tsukuba, Japan: 2002-2003

Postdoctoral Fellow, Pacific Northwest National Lab., Richland, USA: 2003-2004

Visiting Scientist, University of Texas, Austin, USA: 2007

Visiting Professor, CABB, Kerala University, India: 2007~2012

Research Scientist, AIST, Takamatsu, Japan 8/2004-9/2009

Senior Scientist, AIST, Takamatsu, Japan 10/2009~

Adjunct Professor, Department of Environmental Toxicology, Southern University, USA, 2012-2013

PRESTO  (Sakigake) Researcher, Japan Science and Technology Agency 10/2010~3/2014

Guest Professor, Department of Optical Science and Technology, The University of Tokushima, 4/2012~

Guest Professor, Kwansei Gakuin University, 4/2013~

Visiting Scholar, Department of Chemistry, Osaka University, 4/2013~


Editorial Work

Editor, Nano Reviews

Associate Editor, J. Photochem. Photobiol.C: Photochem. Rev.

Associate Editor, Adv. Phys. Chem.

Editorial Board Member, Open Colloid Sci. J.

Editorial Board Member, J. Bioengg. Biomed. Sci.


Academic Societies

Councilor, Japanese Photochemistry Association (JPA)

Director Board Member, Asian Nanoscience and Nanotechnology Association (ANNA)

Fellow, Royal Society of Chemistry

Member, American Chemical Society

Member, Japanese Photochemistry Association

Member, Asian Photochemistry Association

Member, Chemical Society of Japan


As Current/Former Reviewer

Nature Nanotechnology (NPG)

Nature Methods (NPG)

ACS Nano (ACS)

The Journal of Physical Chemistry (ACS)

Journal of the American Chemical Society (ACS)

Langmuir (ACS)

Analytical Chemistry (ACS)

Environmental Science and Technology (ACS)

Crystal Growth and Design (ACS)

ACS Applied Materials and Interfaces (ACS)

Journal of Photochemistry and Photobiology A: Chemistry (Elsevier)

Journal of Photochemistry and Photobiology C: Photochemistry Reviews (Elsevier)

Molecular and Cellular Probes (Elsevier)

Chemical Physics Letters (Elsevier)

Materials Research Bulletin (Elsevier)

Spectrochemica Acta (Elsevier)

Expert Opinion in Medical Diagnosis (Informa Pharmascience)

Current Opinion in Molecular Therapeutics (Thomson Reuters)

Journal of Chemical Physics (AIP)

Applied Physics Letters (AIP)

Macromolecular Chemistry and Physics (Wiley-VCH)

Advanced Functional Materials (Wiley-VCH)


Project Reviewer: Singapore National Research Council (2010~)

Project Reviewer: The Marsden Fund Council, New Zealand (2010~)

Faculty Reviewer: Academia Sinica, Taipei, Taiwan (2010)


I am interested in modern nano and bionano tools and technologies based on multimodal analyses of a wide spectrum of molecules, materials and living systems for the advancement of health technology. The main research area I am focusing at is the use of bioconjugated fluorescent/fluorescent-magnetic nonomaterials and spectroscopy and microscopy, in particular, atomic force microscopy, fluorescence microscopy and time-resolved fluorescence spectroscopy, for the unraveling of subcellular processes and the structures and functioning of cell organelles and biomolecules. For example, currently I am investigating the mechanism underlying the activation of cell signaling molecules, and intracellular delivery of bioconjugated nanoparticles of bioimaging and therapeutic potentials. Also, I am developing novel nano/bionanomaterials, and optimizing their properties for advanced bioanalysis and nanobiotechnology.


Fellow, Royal Society of Chemistry (FRSC), 2011~

Japanese Photochemistry Association Award for Young Scientist, Japan, 2011

Lectureship Price for Young Scientists by the Chemical Society of Japan, 2011

PRESTO Project, Japan Science and Technology Agency (JST), 2010

Distinguished Lectureship Award by the Chemical Society of Japan, 2010.03

Asian and Oceanian Photochemistry Award for Young Scientists, 2010

Most Cited Article Certificate by Analytical and Bioanalytical Chemistry, 2010

The Distinguished Lectureship Award by the Chemical Society of Japan, 2010.03

RCAS Invited Lectureship, Academia Sinica, Taipei, Taiwan, 2009.10.

Invited Scientist, Department of Chemistry and Biochemistry, University of Texas, Austin, 2007

14th Gen-nai prize, Ozaki Foundation, Japan: 2007

Lecture at the Special Symposium on Colloid and Surface Chemistry in the honor of Professor Gabor Somarjai, UC Berkeley, ACS Meeting, San Francisco, USA, 2006.09

PNNL Postdoctoral Fellowship, Pacific Northwest National Laboratory, USA: 2003-2004

JSPS Postdoctoral Fellowship, Nanotechnology Research Institute, AIST, Japan: 2002-2003.

JRCAT Postdoctoral Fellowship, Natl. Instt. Interdiscipl. Res., Japan: 2000-2002

UGC-CSIR Junior and Senior Research Fellowships (NET), Government of India:1995, 96, 97, 98, 99.

Thomas Foundation Top Merit Award, Children’s Friend High School, India: 1987, 88

State Merit Award, Government of Kerala, India: 1985, 1988, 1990.




2217-14 Hayashi-Cho

Takamatsu, Kagawa 761-0395


Phone: (087) 869-3558

Fax: (087) 869-4113

Email: v.biju @

Guest Professor
The University of  Tokushima &
Kwansei Gakuin University

Associate Editor,  J. Photochem.
Photobiol. C: Photochem. Rev.  
Editor, Nano Reviews


Please come back for more images


More pictures coming soon


Propagating single-molecule EGF-EGFR complexes on human ovarian epidermoid carcinoma cells: Amplification of cell signaling


Topography of a Bacteria Expressing Cytochrome


3D Cluster


2D Array of quantum dots on a carbon nanotube

Copyright ACS 2006
Copyright ACS 2006
Copyright ACS 2007
Copyright ACS 2009
Clathrin mediated endocytosis of quantum dots: Colocalization of quantum dots (red)
conjugated with a peptide (allatostatin) and quantum dots (green) conjugated with  clathrin
antibody in human ovarian epidermoid carcinoma cells
Copyright ACS 2009
Copyright ACS 2009
Copyright ACS 2009
Copyright ACS 2009
Copyright ACS 2009

Quantum Dot-DNA

Quantum Dot


pDNA Labeled with Quantum Dots

Nano-Architect: Arranging Nanoparticles

Copyright ACS 2007
Copyright ACS 2008
Copyright ACS 2008
Copyright ACS 2009
Human ovarian epidermoid carcinoma cells
labeled by CdSe-ZnS quantum dots (red)
and Syto16 dye (green)
Quantum dot-peptide
conjugates in 3T3 cells
Quantum dot on the
surface of A431 cells




M. Hamada, N. Takanokoshi, K. Motazaki, Q. Feng, N. Murase, S. Wakida, S. Nakanishi, V. Biju, “In Situ Photochemical Surface Passivation of CdSe/ZnS Quantum Dots for Quantitative Light Emission and Enhanced Photocurrent Response in Solar Cells”, J. Phys. Chem. C 118, 2178–2186 (2014). (Featured on the cover)


V. Biju, “Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy”, Chem. Soc. Rev. 43, 744-764 (2014). (Featured on the cover)


Shibu, E. S., Hamada, M., Nakanishi, S., Wakida, S., Biju, V., “Photoluminescence of CdSe and CdSe/ZnS Quantum Dots: Modifications for Making the Invisible Visible at Ensemble and Single-molecule Levels”, Coord. Chem. Rev., 263-264, 2-12 (2014). (Invited thematic article)


Shibu, E. S.; Sugino, S.; Ono, K.; Saito, H.; Nishioka, A.; Yamamura, S.; Sawada, M.; Nosaka, Y.; Biju, V.Singlet-oxygen-sensitizing near-infrared-fluorescent multimodal nanoparticles”, Angew. Chem. Int. Ed., 52, 10559 –10563, 2013.


Shibu, E. S., Ono, K., Sugino, S., Nishioka, A., Yasuda, A., Shigeri, Y., Wakida, S., Sawada, M., Biju, V., “Photouncaging nanoparticles for MRI and fluorescence imaging in vitro and in vivo”, ACS Nano, 7, 9881-9859 (2013).


Jones, P.; Sugino, S.; Yamamura, S.; Lacy, F.; Biju, V.Impairments of cells and genomic DNA by environmentally transformed engineered nanomaterials”, Nanoscale, 5,  9511-9516, 2013. (Featured on the cover)


Shibu, E. S.; Hamada, M.; Murase, N.; Biju, V.Nanomaterials formulations for photothermal and photodynamic therapy of cancer”, J. Photochem. Photobiol. C: Photochem. Rev., 15, 53-72, 2013. (top 25 hottest articles in Science Direct)


V. Biju, A. Anas, H. Akita, E. S. Shibu, T. Itoh, H. Harashima, M. Ishikawa

FRET from quantum dots to photodecompose undesired acceptors and report the condensation and decondensation of plasmid DNA

ACS Nano, 6, 3776-3788, 2012.


E. S. Shibu, A. Sonoda, Z. Tao, Q. Feng, A. Furube, S. Masuo, L. Wang, N. Tamai, M. Ishikawa, V. Biju

“Photofabrication of fullerene-shelled quantum dots supramolecular nanoparticles for solar energy harvesting”

ACS Nano, 6, 1601-1608, 2012.


V. Biju, T. Itoh, M. Ishikawa

Delivering quantum dots to cells: bioconjugated quantum dots for extracellular and intracellular imaging

Chem. Soc. Rev. 39, 3031-3056,2010 (Highlighted in Chemical Biology, Royal Society)

M. Hamada, S. Nakanishi, T. Itoh, M. Ishikawa, V. Biju

 “Blinking suppression in CdSe/ZnS single quantum dots by TiO2 nanoparticles

ACS Nano, 4, 4445-4454, 2010

N. Kawashima, K. Nakayama, K. Itoh, T. Itoh, M. Ishikawa, V. Biju

“Reversible dimerization of EGFR revealed by single-molecule fluorescence imaging using quantum dots”

Chem. Eur. J., 16, 1186-1192, 2010. (Featured on the Cover)

V. Biju, M. Sathish, R. V. Omkumar, A. Anas, M. Ishikawa

Bioconjugated Quantum Dots for Cancer Research: Present Status, Prospects and Remaining Issues

Biotechnol. Adv., 28, 199-213, 2010.

A. Anas, T. Okuda, N. Kawashima, K. Nakayama, T. Itoh, M. Ishikawa, V. Biju

“Clathrin-mediated endocytosis of quantum dot-peptide conjugates in living cells”

ACS Nano, 3, 2419-2429, 2009. (Highlighted Science and Technology News in C&EN)

V. Biju, T. Itoh, A. Anas, S. Sujith, M. Ishikawa

Semiconductor Quantum Dots and Metal Nanoparticles: Syntheses, Optical Properties, and Biological Applications”

Anal. Bioanal. Chem., 391, 2469–2495, 2008. (top 10 cited article in the journal)

A. Anas, H. Akita, H. Harashima, M. Ishikawa, V. Biju

Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots

J. Phys. Chem. B, 112, 10005-10011, 2008 (Featured on the Front Cover).

R. Kanemoto, A. Anas, Y. Matsumoto, R. Ueji, T. Itoh, Y. Baba, S. Nakanishi, M. Ishikawa, V. Biju

Relations between dewetting of polymer thin films and phase-separation of encompassed quantum dots

J. Phys. Chem. C, 112, 9312-9319, 2008 (Featured on the Front Cover).


Y. Matsumoto, R. Kanemoto, T. Itoh, S. Nakanishi, M. Ishikawa, V. Biju

“Photoluminescence quenching and intensity fluctuations of CdSe-ZnS quantum dots on an Ag nanoparticle film”

J. Phys. Chem. C, 112, 1345-1350, 2008 (Featured on the Front Cover).


V. Biju, R. Kanemoto, Y. Matsumoto, S. Ishii, T. Itoh, S. Nakanishi, Y. Baba, M. Ishikawa

“Photoinduced photoluminescence variations of CdSe quantum dots in polymer solutions”

J. Phys. Chem. C, 111, 7924-7932, 2007 (Featured on the Front Cover).

V. Biju, Y. Makita, A. Sonoda, H. Yokoyama, Y. Baba, M. Ishikawa

“Temperature-sensitive photoluminescence of CdSe quantum dot clusters”

J. Phys. Chem. B, 109, 13899-13905, 2005  (Featured on the Front Cover).

V. Biju, M. Micic, D. Hu, H. P. Lu

“Intermittent single-molecule interfacial electron transfer dynamics”

J. Am. Chem. Soc., 126, 9374-9381, 2004.