Tsukuru MINAMIKI, Ph.D.

Research Scientist
Nano-Biodevice Research Group, Health and Medical Research Institute
National Institute of Advanced Industrial Science and Technology (AIST)


E-mail: t.minamiki[at]aist.go.jp

ORCiD (ORCID ID: 0000-0003-3136-0431)

Publons (Researcher ID: N-8701-2016)


Education

Yamagata University, Japan
/ Ph.D., Organic Materials Engineering, 2016 (Supervisor: Prof. Shizuo Tokito)
/ M.E., Organic Device Engineering, 2014
/ B.E., Polymer Science and Engineering, 2012
Hakodate National College of Technology, Japan
/ A.E., Material and Environmental Engineering, 2010 (Supervisor: Prof. Makoto Hino)


Academic Appointments

National Institute of Advanced Industrial Science and Technology (AIST), Japan
/ Research Scientist, Health and Medical Research Institute, 2020 - Present
/ Research Scientist, Biomedical Research Institute, 2018 - 2020
Institute of Industrial Science, The University of Tokyo, Japan
/ Postdoctoral Research Fellow of Japan Society for the Promotion of Science (JSPS PD), 2016-2018 (Advisor: Prof. Tsuyoshi Minami)
Yamagata University, Japan
/ Research Fellow of Japan Society for the Promotion of Science (JSPS DC), 2016 (Advisor: Prof. Shizuo Tokito)


Research Interests

Organic Electronics / Molecular Assemblies / Surface Sciences / Chemical Sensors

Publications


See also, Google Scholar Citations


36. Flexible organic thin-film transistor immunosensor printed on a one-micron-thick film
Minamiki, T.; Minami, T.; Chen, Y.-P.; Mano, T.; Takeda, Y.; Fukuda, K.; Tokito, S.
Comms. Mater. 2021, 2, 8.


35. A Water-Gated Organic Thin-Film Transistor for Glyphosate Detection: A Comparative Study with Fluorescence Sensing
Sasaki, Y.; Asano, K.; Minamiki, T.; Zhang, Z.; Takizawa, S.; Kubota, R.; Minami, T.
Chem. Eur. J. 2020, 26, 1-6.
(This article was selected as a Very Important Paper and a Cover Picture.)


34. The Power of Assemblies at Interfaces: Nanosensor Platforms Based on Synthetic Receptor Membranes
Minamiki, T.*; Ichikawa, Y.; Kurita, R.*
Sensors 2020, 20, 2228. (Review)
(This article was selected as an Issue Cover.)


33. Protein Assays on Organic Electronics: Rational Device and Material Designs for Organic Transistor-Based Sensors
Minamiki, T.; Kubota, R.; Sasaki, Y.; Asano, K.; Minami, T.
ChemistryOpen 2020, 9, 573-581. (Minireview)


32. Systematic Investigation of Molecular Recognition Ability in FET-Based Chemical Sensors Functionalized with a Mixed Self-Assembled Monolayer System
Minamiki, T.*,+; Ichikawa, Y.+; Kurita, R.*
ACS Appl. Mater. Interfaces 2020, 12, 15903-15910.
(+These authors contributed equally to this paper.)


31. Microfluidic System with Extended-Gate-Type Organic Transistor for Real-Time Glucose Monitoring
Didier, P.; Lobato-Dauzier, N.; Clément, N.; Genot, A. J.; Sasaki, Y.; Leclerc, É; Minamiki, T.; Sakai, Y.; Fujii, T.; Minami, T.
ChemElectroChem 2020, 7, 1332-1336.
(This article was selected as a Cover Feature.)


30. An Extended-Gate Type Organic Transistor with a Solution Processable Small-Molecule Semiconductor Capable of Detecting Glutathione in Water
Asano, K.; Aiko, M.; Yamanashi, Y.; Sasaki, Y.; Nakahara, K.; Minamiki, T.; Koike, T.; Minami, T.
Jpn. J. Appl. Phys. 2020, 59, SGGG07.


29. Chemical Sensing Platforms Based on Organic Thin-Film Transistors Functionalized with Artificial Receptors
Kubota, R.; Sasaki, Y.; Minamiki, T.; Minami, T.
ACS Sens. 2019, 10, 2571-2587. (Perspective)
(This article was selected as a Supplementary Cover.)


28. Potentiometric detection of biogenic amines utilizing affinity on a 4-mercaptobenzoic acid monolayer
Minamiki, T.*; Kurita, R.*
Anal. Methods 2019,11, 1155-1158.
(This article was selected as an Outside Front Cover. / Invited Paper for Special Issue on "Electrochemistry for health applications")


27. An Organic FET with an Aluminum Oxide Extended Gate for pH Sensing
Minamiki, T.; Sekine, T.; Aiko, M; Su, S.; Minami, T.
Sens. Mater. 2019, 31, 99-106.


26. Fabrication of a Flexible Biosensor based on an Organic Field-effect Transistor for Lactate Detection
Minamiki, T.; Tokito, S.; Minami, T.
Anal. Sci. 2019, 35, 103-106.


25. Development of polymer field-effect transistor-based immunoassays
Minamiki, T.; Sasaki, Y.; Su, S.; Minami, T.
Polym. J. 2019, 51, 1-9. (Focus Review)
(This article was selected as a Featured Article.)


24. Development of Enzymatic Sensors Based on Extended-gate-type Organic Field-effect Transistors
Minami, T.; Minamiki, T.; Sasaki, Y.
Electrochemistry 2018, 86, 303-308. (Comprehensive Paper)
(This article was selected as a Feature Article.)


23. An electrolyte-gated polythiophene transistor for the detection of biogenic amines in water
Minamiki, T.; Hashima, Y.; Sasaki, Y.; Minami, T.
Chem. Commun. 2018, 54, 6907–6910.
(This article was advertised by the ChemComm Official Twitter Account.)


22. An organic transistor-based electrical assay for copper(II) in water
Sasaki, Y.; Minami, T.; Minamiki, T.; Tokito, S.
Electrochemistry 2017, 85, 775–778.


21. A molecular self-assembled colourimetric chemosensor array for simultaneous detection of metal ions in water
Sasaki, Y.; Minamiki, T.; Tokito, S.; Minami, T.
Chem. Commun. 2017, 53, 6561–6564.
(This article was selected as an Inside Front Cover article.)


20. Label-Free Direct Electrical Detection of a Histidine-Rich Protein with Sub-Femtomolar Sensitivity using an Organic Field-Effect Transistor
Minamiki, T.+; Sasaki, Y.+; Tokito, S.; Minami, T.
ChemistryOpen 2017, 6, 472–475.
(+These authors contributed equally to this paper. / This article was selected as a Front Cover article. / This article was also selected as one of the top downloaded article in 2017-2018.)


19. Label-Free Detection of Human Glycoprotein (CgA) Using an Extended-Gated Organic Transistor-Based Immunosensor
Minamiki, T.; Minami, T.; Sasaki, Y.; Wakida, S.; Kurita, R.; Niwa, O.; Tokito, S.
Sensors 2016, 16, 2033.


18. Selective nitrate detection by an enzymatic sensor based on an extended-gate type organic field-effect transistor
Minami, T.; Sasaki, Y.; Minamiki, T.; Wakida, S.; Kurita, R.; Niwa, O.; Tokito, S.
Biosens. Bioelectron. 2016, 81, 89–91.


17. Electric Detection of Phosphate Anions in Water by an Extended-Gate Type Organic Field-Effect Transistor Functionalized by a Zinc(II)-Dipicolylamine Derivative
Minami, T.; Minamiki, T.; Tokito, S.
Chem. Lett. 2016, 45, 371–373.


16. Detection of Mercury (II) Ion in Water using an Organic Field Effect Transistor with a Cysteine-immobilized Gold Electrode
Minami, T.; Minamiki, T.; Tokito, S.
Jpn. J. Appl. Phys. 2016, 55, 04EL02.


15. Antibody- and Label-Free Phosphoprotein Sensor Device Based on an Organic Transistor
Minamiki, T.; Minami, T.; Koutnik, P.; Anzenbacher, Jr., P.; Tokito, S.
Anal. Chem. 2016, 88, 1092–1095.


14. A mercury (II) ion sensor device based on an organic field effect transistor with an extended-gate modified by dipicolylamine
Minami, T.; Sasaki, Y.; Minamiki, T.; Koutnik, P.; Anzenbacher, Jr., P.; Tokito, S.
Chem. Commun. 2015, 51, 17666–17668.
(This article was selected as a Back Cover article.)


13. An Organic Field-Effect Transistor with an Extended-Gate Electrode Capable of Detecting Human Immunoglobulin A
Minamiki, T.; Minami, T.; Sasaki, Y.; Kurita, R.; Niwa, O.; Wakida, S.; Tokito, S.
Anal. Sci. 2015, 31, 725–728.
(This article was selected as The TOP 3 most cited papers of Analytical Sciences in 2016.)


12. An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in an Aqueous Solution
Minami, T.; Sato, T.; Minamiki, T.; Tokito, S.
Anal. Sci. 2015, 31, 721–724.
(This article was selected as a Hot Article.)


11. A novel OFET-based biosensor for the selective and sensitive detection of lactate levels
Minami, T.; Sato, T.; Minamiki, T.; Fukuda, K.; Kumaki, D.; Tokito, S.
Biosens. Bioelectron. 2015, 74, 45–48.


10. Anion Sensor Based on Organic Field Effect Transistor
Minami, T.; Minamiki, T.; Tokito, S.
Chem. Commun. 2015, 51, 9491–9494.


9. Printed Organic Transistors with Uniform Electrical Performance and Their Application to Amplifiers in Biosensor
Fukuda, K.; Minamiki, T.; Minami, T.; Watanabe, M.; Fukuda, T.; Kumaki, D.; Tokito, S.
Adv. Electron. Mater. 2015, 1, 1400052.
(This article was selected as a Back Cover article.)


8. Extended-gate organic field-effect transistor for the detection of histamine in water
Minamiki, T.; Minami, T.; Yokoyama, D.; Fukuda, K.; Kumaki, D.; Tokito, S.
Jpn. J. Appl. Phys. 2015, 54, 04DK02.


7. Cysteine detection in water using an organic field-effect transistor with a gold extended-gate electrode
Minami, T.; Minamiki, T.; Fukuda, K.; Kumaki, D.; Tokito, S.
Jpn. J. Appl. Phys. 2015, 54, 04DK01.


6. A Label-Free Immunosensor for IgG Based on an Extended-Gate Type Organic Field Effect Transistor
Minamiki, T.; Minami, T.; Kurita, R.; Niwa, O.; Wakida, S.; Fukuda, K.; Kumaki, D.; Tokito, S.
Materials 2014, 7, 6843–6852.


5. An extended-gate type organic field effect transistor functionalized by phenylboronic acid for saccharide detection in water
Minami, T.; Minamiki, T.; Hashima, Y.; Yokoyama, D.; Sekine, T.; Fukuda, K.; Kumaki, D.; Tokito, S.
Chem. Commun. 2014, 50, 15613–15615.


4. Accurate and reproducible detection of proteins in water using an extended-gate type organic transistor biosensor
Minamiki, T.; Minami, T.; Kurita, R.; Niwa, O.; Wakida, S.; Fukuda, K.; Kumaki, D.; Tokito, S.
Appl. Phys. Lett. 2014, 104, 243703.
(This article was selected as the Most Read article in 2016, the Most Accessed articles in 2014-2015 in Biophysics and Bio-Inspired Systems from Applied Physics Letters.)


3. syn-/anti-Anthradithiophene Derivative Isomer Effects on Semiconducting Properties
Mamada, M.; Katagiri, H.; Mizukami, M.; Honda, K.; Minamiki, T.; Teraoka, R.; Uemura, T.; Tokito, S.
ACS Appl. Mater. Interfaces 2013, 5, 9670–9677.


2. Strain sensitivity and durability in p-type and n-type organic thin-film transistors with printed silver electrodes
Fukuda, K.; Hikichi, K.; Sekine, T.; Takeda, Y.; Minamiki, T.; Kumaki, D.; Tokito, S.
Sci. Rep. 2013, 3, 2048.


1. Synthesis, Physical Properties, and Field-Effect Mobility of Isomerically Pure syn-/anti-Anthradithiophene Derivatives
Mamada, M.; Minamiki, T.; Katagiri, H.; Tokito, S.
Org. Lett. 2012, 14, 4062–4065.

Research Grants

Grant-in-Aid for Early-Career Scientists / Principal Investigator (FY2020-2021)

Grant-in-Aid for Young Scientists (B) / Principal Investigator (FY2017-2018)

Grant-in-Aid for Challenging Research (Exploratory) / Co-Investigator (PI: Ryoji Kurita) (FY2017-2018)

Grant-in-Aid for JSPS Fellows / Research Fellow (FY2016-2017)


The Precise Measurement Technology Promotion Foundation / Principal Investigator (FY2021)

Fuji Seal Foundation / Principal Investigator (FY2021)

Ozawa and Yoshikawa Memorial Electronics Research Foundation / Principal Investigator (FY2020)

Iketani Science and Technology Foundation / Co-Investigator (PI: Ryoji Kurita) (FY2020)

Mishima Kaiun Memorial Foundation / Principal Investigator (FY2019-2020)

Kawamura Scholarship Foundation / Principal Investigator (FY2015)