Clock Gene in Animal Update: 2009.3.16 Site Map
List of clock genes Outline of clock genes Animal model Functional domains List of animals

Domain of Clock Gene Product

Domain Protein Description SMART InterPro
PAS PERIOD
CLOCK
ARNTL[BMAL] (CYC)
PAS (PERIOD ARNT SIM) domains were found in proteins involved in sensing for  environmental signals. SM00091 IPR000014
PAC PERIOD
CLOCK
ARNTL
PAC (PAS-associated, C-terminal) domains were found in C-terminal of PAS domains. SM00086 IPR001610
bHLH CLOCK
ARNTL
DEC, CWO
bHLH (basic Helix-Loop-Helix ) is a DNA binding domain. SM00353 IPR001092
Orange DEC, CWO Orange domain is conserved in Hairy/E(SPL) family. SM00511 IPR003650
bZIP (BRLZ) NFIL3 [E4BP4]
(PDP1)
bZIP (basic-leucine ZIPper; BRLZ, Basic Region Leucin Zipper) is a DNA binding domain. SM00338 IPR004827
zf-C4 (ZnF_C4) ROR
NF1D1 [REV-ERB]
zf-C4 (c4 zinc finger in nuclear hormone receptors) is a DNA binding domain. SM00399 IPR001628
HOLI ROR
NF1D1 [REV-ERB]
HOLI (Ligand binding domain of hormone receptors) SM00430 IPR000536
S_TKcGSK3 (SHAGGY)
CSNK2A
Serine/Threonine protein kinases, catalytic domainSM00220IPR002290
FBOX BRCT [FWD1] (SLMB)
FBXL3
JETLAG
FBOX is a receptor for ubiquitination targets. SM00256 IPR001810
WD40 BRCT, SLMB WD40 is involved in protein-protein interaction. SM00320 IPR001680

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