last updated 2024.1.29

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Profile
Ryo Kosaka (Dr. Eng.)
National Institute of Advanced Industrial Science and Technology (AIST)
Senior Plannning Manager, Research Strategy Planning Department, Planning Headquarters Technology Policy Office
Artificial Organs Group, Health and Medical Research Institute（website）
Team Leader in New-generation Medical Treatment and Diagnosis Research Laboratory（website）
1-1-1 Umezono, Tsukuba, Ibaraki 305-8560 JAPAN
E-mail：ryo.kosaka*aist.go.jp（Change "*" to "@")
Personal profile
  • 1996-2000 College of Engineering Systems, University of Tsukuba
  • 2000 (US) Research Associate, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA
  • 2003-2005 Doctoral Research Fellow (DC2) of the Japan Society for the Promotion of Science (JSPS)
  • 2000-2005 Graduate School of Systems and Information Engineering, Univ. of Tsukuba, (Sankai LAB), Ph.D.
  • 2005-2012 Researcher, National Institute of Advanced Industrial Science and Technology (AIST)
  • 2013-2014 (DE) Research Associate, RWTH Aachen University Helmholtz Institute, Aachen, Germany
  • 2015-2016 Deputy Director, Ministry of Economy Trade and Industry (METI), Japanese Government, Tokyo
  • 2012-2021 Senior Researcher, Artificial Organs Group, Health and Medical Research Institute, AIST
  • 2020- Team Leader in New-generation Medical Treatment and Diagnosis Research Laboratory, AIST
  • 2021-2022 Chief Senior Artificial Organs Group, Researcher in Health and Medical Research Institute, AIST
  • 2023 Group Leader, Artificial Organs Group, Health and Medical Research Institute, AIST
  • 2024- Senior Planning Manager, Research Strategy Planning Department, AIST
Research topics
  • ●Development of a hydrodynamically levitated centrifugal blood pump
  • We have developed a non-contact-type centrifugal blood pump with hydrodynamic bearings for mechanically circularly assist (MCA). The impeller levitates by means of an original spiral-groove thrust bearing and a journal bearing, without any additional displacement-sensing module or additional complex control circuits. The pump was improved by optimizing the design of the thrust bearing and the radial bearing.

Blood pump



  • ●Development of an Ex-Vivo Lung Perfusion (EVLP)
Lung transplantation is an established treatment for advanced pulmonary disease. In spite of the use of marginal donors and donation after circulatory death (DCD) donors as well as aggressive organ donor management, the utilization of donor lungs is still limited to 20% in the USA. Ex vivo lung perfusion (EVLP) is an emerging technique applied to donor lungs outside of the body before transplantation and preserves and evaluates lung function. However, there is no established protocol in EVLP to identify transplantable lungs. The purpose of the project is to develop EVLP system for a non-invasive evaluation and preservation of donor lungs and evaluate in animal experiments using a porcine model.

Ex-vivo lung perfusion
  • ●Development of a Miniaturized Mass Flow Meter
In order to grasp the conditions of patients and implantable artificial hearts, it is essential for monitoring the blood flow rate continuously and noninvasively. However it is difficult to monitor the pump flow rate in an implantable artificial heart, because the conventional flow meter is too large to implant into the human body, and the flow estimation method is influenced by changes in the blood characteristics and the pump performance. In particular, the power consumption has neither linearity nor uniqueness with respect to the pump flow rate in an axial flow blood pump. In this research, we develop a prototype miniaturized mass-flow meter that uses centrifugal force for discharged patients with an axial flow blood pump.

Flow meter

●Past study
・Evaluation method for three dimensional regenerated cartilage
・Development of a long-term disposable blood pump
・Development of hydrodynamic bearing for blood pump
・Online Parameter Identification of Systemic Circulation Using Delta-Operator
・Tsukuba-Telemetry System for Continuous Flow Artificial Heart
・An Operating Point Control System For a Continuous-Flow Artificial Heart
Achievement

1．Original Papers

  1. Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T. "Online Parameter Identification of Systemic Circulation using Delta-Operator", Artif Organs, 26(8), 723-726, 2002
  2. Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T. "Online Parameter Identification for Second Order Physiological Systemic Circulation Model using Delta-Operator", Artif Organs, 26(11), 967-970, 2002
  3. Kosaka R, Yanagi K, Sato T, Ishitoya H, Ichikawa S, Motomura T, Kawahito S, Mikami M, Linneweber J, Nonaka K, Takano T, Glueck J, Sankai Y, Nose' Y. "An Operating Point Control System For a Continuous-Flow Artificial Heart: In-Vitro study", ASAIO J, 49(3), 259-264, 2003
  4. Kosaka R, Sankai Y, Takiya R, Jikuya T, Yamane T, Tsutsui T. "Tsukuba Remote Monitoring System for Continuous-Flow Artificial Heart", Artif Organs, 27(10), 897-906, 2003Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T. "Resonant Frequency Control Method for the Artificial Heart using Online Parameter Identification", Artif Organs、28(10), 921-926, 2004
  5. Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T. "Estimation of a physiologic strategy based on a mathematical model for assisting and substituting cardiac functions by a robotic artificial heart", ADVANCED ROBOTICS, 19-7, 735-749, 2005
  6. Kosaka R, Nishida M, Maruyama O, Yamane T. "Development of miniaturized mass-flow meter for an axial flow blood pump", Artif Organs, 31(5), 412-419, 2007
  7. Yamane t, Maruyama O, Nishida, Kosaka R, Sugiyama D, Miyamoto Y, Kawamura H, Kato T, Sano T, Okubo T, Sankai Y, Shigeta O, Tsutsui, T. "Hemocompatibility of a hydrodynamic levitation centrifugal blood pump", J Artif Organs, 10(2), 71-76, 2007
  8. Kosaka R, Sankai Y, Yamane T, Tsutsui T. "Resonant Frequency Control Method for Total Artificial Heart in-Vitro Study". Artif Organs，32(2)，157-160, 2008
  9. Yamane t, Maruyama O, Nishida, Kosaka R, Chida T, Kawamura H, Kuwana K, Ishihara K, Sankai Y, Matsuzaki M, Shigeta O, Enomoto Y, Tsutsui, T. "Antithrombogenic Properties of a Monopivot Magnetic-Suspension Centrifugal Pump for Circulatory Assist", Artif Organs, 32(6), 484-489, 2008
  10. Yamane t, Nonaka K, Miyoshi H, Maruyama O, Nishida, Kosaka R, Sankai Y, Tsutsui T. "Pivot wear of a centrifugal blood pump developed for circulatory assist", J Artif Organs, 11(4), 232-237, 2008
  11. Nishida M, Maruyama O, Kosaka R, Kogure H, Kawamura H, Yamamoto Y, Sankai Y, Tsutsui T, Kuwana K. "Hemo-compatibility Evaluation with Experimental and Computational Fluid Dynamic Analyses for a Monopivot Circulatory Assist Pump ", Artif Organs, 33(4), 378-386, 2009
  12. Kosaka R, Maruyama O, Nishida M, Saito S, Hirai S, Yamane T. "Improvement of Hemocompatibility in a Centrifugal Blood Pump with Hydrodynamic Bearings and a Semi-Open Impeller", Artif Organs, 33(10), 798-804, 2009
  13. Kosaka R, Nishida M, Maruyama O, Yamane T. "Development of a miniaturized mass-flow meter for an axial flow blood pump based on computational analysis", J Artif Organs, 14(3), 178-184, 2011
  14. Yamane T, Maruyama O, Nishida M, Kosaka R. "Research and development of a monopivot centrifugal blood pump", Synthesiology, 5 (1), 16-24, 2012
  15. Kosaka R, Nishida M, Maruyama O, Yambe T, Imachi K, Yamane T. "Effect of a bearing gap on hemolytic property in a hydrodynamically levitated centrifugal blood pump with a semi-open impeller", BMME, 23 (1-2), 37-47, 2013
  16. He F, Wang X, Maruyama O, Kosaka R, Sogo Y, Ito A, Ye J. Sankai Y, Tsutsui T. "Improvement in endothelial cell adhesion and retention under physiological shear stress using a laminin-apatite composite layer on titanium", Journal of the Royal Society Interface 10 (81), 2013
  17. Yamane T, Kosaka R, Nishida M, Maruyama O, Yamamoto Y, Kuwana K, Kawamura H, Shiraishi Y, Yambe T, Sankai Y, Tsutsui T. "Enhancement of Hemocompatibility of the MERA Monopivot Centrifugal Pump: Toward Medium-Term Use", Artif Organs 37(2), 217-221, 2013
  18. Wang X, He F, Li X, Ito A, Sogo Y, Maruyama O, Kosaka R, Ye J. "Tissue-engineered endothelial cell layers on surface-modified Ti for inhibiting in vitro platelet adhesion", Sci. Technol. Adv., 14(3), 2013
  19. Kosaka R, Yada T, Nishida M, Maruyama O, K, Yamane T. "Geometric optimization of a step bearing for a hydrodynamically levitated centrifugal blood pump for the improvement of hemolysis level", Artif Organs, 37(9), 778-785, 2013
  20. Yasui K, Kosaka R, Nishida M, Maruyama O, K, Kawaguchi Y, Yamane T. "Optimal design of the hydrodynamic multi-arc bearing in a centrifugal blood pump for the improvement of bearing stiffness and hemolysis level", Artif Organs, 37 (9), 768-777, 2013
  21. Kosaka R, Yasui K, Nishida M, Maruyama O, K, Kawaguchi Y, Yamane T. "Optimal bearing gap of a multi-arc radial bearing in a hydrodynamically levitated centrifugal blood pump for the reduction of hemolysis", Artif Organs, 38 (9), 818-822, 2014
  22. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O. "Feasibility of the optical imaging of thrombus formation in a rotary blood pump by near-infrared light", Artif Organs, 38 (9), 733-740, 2014
  23. Asakura Y, Sapkota A, Maruyama O, Kosaka R, Yamane T, Takei M. "Relative permittivity measurement during the thrombus formation process using the dielectric relaxation method for various hematocrit values", J Artif Organs, 18 (4), 346-353, 2015
  24. Murashige T, Kosaka R, Nishida M, Maruyama O, Kawaguchi Y, Yamane T, "Evaluation of a spiral groove geometry for improvement of hemolysis level in a hydrodynamically levitated centrifugal blood pump", Artif Organs. 39 (8), 710-714, 2015
  25. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O, Kawaguchi Y, Yamane T, "Real‐time observation of thrombus growth process in an impeller of a hydrodynamically levitated centrifugal blood pump by near‐infrared hyperspectral imaging", Artif Organs. 39 (8), 714-719, 2015
  26. Misawa M, Nitta N, Shirasaki Y, Hayashi K, Kosaka R, Hyodo K, Numano T, Homma K, Kuribayashi S, Fujihara Y, Hoshi K, "Characteristic X-ray absorptiometry applied to the assessment of tissue-engineered cartilage development", Journal of X-Ray Science and Technology, 23(4), 489-502 (2015)
  27. Fujihara Y, Nitta N, Misawa M, Hyodo K, Shirasaki Y, Hayashi K, Kosaka R, Homma K, Numano T, Kuribayashi S, Watanabe Y, Sato J, Ohtomo K, Takato T, Hoshi K. "T2 and ADC of MRI Reflect Maturation of Tissue-engineered Cartilage Subcutaneously Transplanted in Rats", Tissue Eng Part C Methods, 22(5), 1-10 (2016)
  28. Maruyama O, Kosaka R, Nishida M, Yamane T, Tatsumi E, Taenaka Y. "In vitro thrombogenesis resulting from decreased shear rate and blood coagulability", J Artif Organs, 39(4), 194-4 (2016)
  29. Fujihara Y, Nitta N, Misawa M, Hyodo K, Shirasaki Y, Hayashi K, Kosaka R, Homma K, Numano T, Kuribayashi S, Watanabe Y, Sato J, Ohtomo K, Takato T, Hoshi K. "T2 and Apparent Diffusion Coefficient of MRI Reflect Maturation of Tissue-Engineered Auricular Cartilage Subcutaneously Transplanted in Rats", Tissue Eng Part C Methods, 22(5), 429-38 (2016)
  30. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O. "Optical aggregometry of red blood cells associated with the blood-clotting reaction in extracorporeal circulation support", J Artif Organs, 19(3), 241-248 (2016)
  31. Nishida M, Negishi T, Sakota D, Kosaka R, Maruyama O, Hyakutake T, Kuwana K, Yamane T. "Effect of Impeller Geometry on Lift-Off Characteristics and Rotational Attitude in a Monopivot Centrifugal Blood Pump", Artif Organs, 40 (6), E89-E101 (2016)
  32. Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Yamane T, Maruyama O "Plasma Skimming in a Spiral Groove Bearing of a Centrifugal Blood Pump", Artif Organs, 40 (9), 856-66 (2016)
  33. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O. "Noninvasive optical imaging of thrombus formation in mechanical circulatory support devices", Journal of Biorheology，30 (1), 6-12 (2016)
  34. Nishida M, Negishi T, Sakota D, Kosaka R, Maruyama O, Hyakutake T, Kuwana K, Yamane T. "Properties of a monopivot centrifugal blood pump manufactured by 3D printing", J Artif Organs, 19 (4), 322-329 (2016)
  35. Nishida M, Kosaka R, Maruyama O, Yamane T, Shirasu A, Tatsumi E, Taenaka Y. "Long-term durability test of axial-flow ventricular assist device under pulsatile flow", J Artif Organs, 20 (1), 26-33 (2017)
  36. Sakota D, Fujiwara T, Ohuchi K, Kuwana K, Ymazaki H, Kosaka R, Nishida M, Mizuno T, Arai H and Maruyama O. "Development of a real-time and quantitative thrombus sensor for an extracorporeal centrifugal blood pump by near-infrared light"，Biomedical Optics Express，9(1)，190-201(2018),
  37. Sakota D, Kondo K, Kosaka R, Nishida M, Maruyama O. "Plasma skimming efficiency of human blood in the spiral groove bearing of a centrifugal blood pump", J Artif Organs, 24. 126-34 (2020)
  38. Morita N, Sakota D, Ohta A, Kosaka R, Maruyama O, Nishida M, Kondo K, Takeshita T, Iwasaki W. "Real-time, non-invasive thrombus detection in an extracorporeal circuit using micro-optical thrombus sensors", Int J Artif Organs. 44(8). 565-73 (2020)
  39. Yamane T, Adachi K, Kosaka R, Maruyama O, Nishida M. "Suitable hemolysis index for low-flow rotary blood pumps". J Artif Organs. 24(2), 120-5 (2020)
  40. Kosaka R, Sakota D, Nishida M, Maruyama O, Yamane T. "Improvement of hemolysis performance in a hydrodynamically levitated centrifugal blood pump by optimizing a shroud size", J Artif Organs. 24. 157-63 (2021)
  41. Harada T, Tanoue Y, Oishi Y, Sonoda H, Kimura S, Fujita S, Ushijima T, Kosaka R, Kojima K, Shiose A, "Investigating the Cause of Hemolysis in Patients Supported by a Pulsatile Ventricular Assist Device", Heart Vessels, 36(6). 890-8 (2021)
  42. Oota-Ishigaki A, Yamane T, Sakota D, Kosaka R, Maruyama O, Nishida M, "In vitro hemocompatibility investigation for the development of low-flow centrifugal blood pumps with less platelet clogging", Int J Artif Organs, 45(4). 431-7 (2021)
  43. Oota-Ishigaki A, Maruyama O, Sakota D, Kosaka R, Yamane T, Nishida M, "Quantitative investigation of platelet aggregation under high shear force for anti-platelet aggregation in vitro tests", Int J Artif Organs, 44(10). 687-93 (2021)
  44. Satako D, Kosaka R, et al. Optical oxygen saturation imaging in cellular ex vivo lung perfusion to assess lobular pulmonary function. Biomed Opt Express. 2021 Dec 14;13(1):328-343 (2021)
  45. Ming J, Sakota D, Koaska R, Hijikata W. "Optical oxygen saturation imaging in cellular ex vivo lung perfusion to assess lobular pulmonary function". J Artif Organs. 25(3). 195-203 (2022).
  46. Kosaka R, Sakota D, Niikawa H, Ohuchi K, Arai H, McCurry KR, Okamoto T. Lung thermography during the initial reperfusion period to assess pulmonary function in cellular ex vivo lung perfusion. Artif Organs. 45(4). 431-7 (2022)
  47. Kosaka R, Sakota D, Sakanoue I, Niikawa H, Ohuchi K, Arai H, McCurry KR, Okamoto T. Real-time Lung Weight Measurement During Cellular Ex Vivo Lung Perfusion: An Early Predictor of Transplant Suitability. Transplantation. 107(3):628-638 (2023)
  48. Sakota D, Kosaka R, Nagaoka E, Ohuchi K, Tahara T, Arai H, Sakanoue I, McCurry KR, Okamoto T. Left ventricular assist device mode: Co-pulse left ventricular unloading in a working mode of ex vivo heart perfusion. JHLT, in press (2023)

2．Proceedings

  1. Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T, "Online Parameter Identification of Systemic Circulation using Delta-Operator in Animal Experiment", Proc. of IEEE/RSJ IROS 2002, pp.1469-1474, 2002/09
  2. Kosaka R, Sankai Y, Jikuya T, Yamane T, Tsutsui T, "Estimation of Physiological Parameters during Animal Experiment with Left Ventricular Assist System", Proc. of IEEE EMBS-BMES 2002, pp.1571-1572, 2002/10
  3. Kosaka R, Yada T, Maruyama O, Nishida M, Saito S, Hirai S, Yamane T. "Improvement of Hemolysis in a Centrifugal Blood Pump with Hydrodynamic Bearings and Semi-Open Impeller", Proceedings of the IEEE Engineering in Medicine and Biology Society 2007, pp.3982-3985, 2007/08
  4. Kosaka R, Nishida M, Maruyama O, Yamane T. "Development of Miniaturized Mass-Flow Meter for an Axial Flow Blood Pump using a Curved Cannula", Proceedings of the IEEE Engineering in Medicine and Biology Society 2010, pp.2513-2516, 2010/08
  5. Kosaka R, Nishida M, Maruyama O, Yamane T. "Noninvasive miniaturized mass-flow meter using a curved cannula for implantable axial flow blood pump", Proceedings of the IEEE Engineering in Medicine and Biology Society 2011, pp.1343-1346, 2011/8
  6. Kosaka R, Yada T, Nishida M, Maruyama O, Yamane T. "Improvement of hemocompatibility for hydrodynamic levitation centrifugal pump by optimizing step bearings", Proceedings of the IEEE Engineering in Medicine and Biology Society 2011, pp.1331-1334, 2011/8
  7. Murashige T, Kosaka R, Nishida M, Maruyama O,Kuwana K, Kawaguchi Y, Yamane T. "Effect of Flow Conditions in Bearing Gaps on the Hemolytic Property in a Hydrodynamically Levitated Centrifugal Blood Pump", Proceedings of the IEEE Engineering in Medicine and Biology Society 2013, pp.2732-2735. 2013/7
  8. Kosaka R, Fukuda K, Nishida M, Maruyama O, Yamane T. "Noninvasive Blood-Flow Meter Using a Curved Cannula with Zero Compensation for an Axial Flow Blood Pump", Proceedings of the IEEE Engineering in Medicine and Biology Society 2013, pp.4090-4093. 2013/7
  9. Sapkota A, Asakura Y, Maruyama O, Kosaka R, Yamane T, Takei M. "Risk analysis and detection of thrombosis by measurement of electrical resistivity of blood", Proceedings of the IEEE Engineering in Medicine and Biology Society 2013, pp.4086-4089. 2013/7
  10. Nishida M, Nakayama K, Kosaka R, Maruyama O, Kawaguchi Y, Kuwana K, Yamane T. "Effect of impeller flow path on pump performance and impeller stability of the monopivot circulatory pump", Proceedings of the IEEE Engineering in Medicine and Biology Society 2013, pp.2736-2739. 2013/7
  11. Sakota D, Kani Y, Kosaka R, Nishida M, Maruyama O. "Simultaneous determination of hemolysis and hematocrit in extracorporeal circulation by plasma surface reflectance spectroscopy", Proceedings of the IEEE Engineering in Medicine and Biology Society 2013, pp.6764-6767. 2013/7
  12. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O, "Evaluation of erythrocyte flow at a bearing gap in a hydrodynamically levitated centrifugal blood pump", Proceedings of the IEEE Engineering in Medicine and Biology Society 2015, pp.270-273. 2015/8
  13. Sakota D, Kosaka R, Nishida M, Maruyama O."Development of a photon-cell interactive Monte Carlo simulation for non-invasive measurement of blood glucose level by Raman spectroscopy", Proceedings of the IEEE Engineering in Medicine and Biology Society, pp.6409-6412, 2015/08
  14. Kosaka R, Yoshida F, Nishida M, Maruyama O, Kawaguchi Y, Yamane T. "Bearing gap adjustment for improvement of levitation performance in a hydrodynamically levitated centrifugal blood pump", Proceedings of the IEEE Engineering in Medicine and Biology Society. pp.3295-3298、2015/08
  15. Kawakami K, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Maruyama O. "Reaction mechanism of blood coagulation factors in shear flow field". Proceedings of the IEEE Engineering in Medicine and Biology Society, pp.4309-4312, 2016/08.
  16. Sakota D, Fujiwara T, Ohuchi K, Kuwana K, Yamasaki H, Kosaka R, Maruyama O. "Development of real-time and quantitative monitoring of thrombus formation in an extracorporeal centrifugal blood pump". Proceedings of SPIE，10501-，pp.1-6、2018/02.
  17. Morita N, Sakota D, Ohta A, Kosaka R, Maruyama O, Nishida M, Kondo K, Takeshita T, Iwasaki W. "OPTICAL BLOOD CLOTTING SENSOR FOR AN ARTIFICIAL CIRCULATION APPARATUS", 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)，-，pp.2197-2200、2019/06

3．Awards

  1. "ISRP 2002 Poster Presentation Award", 10th Congress of ISRP, Kosaka R, Yamane T, Sankai Y, et al., 2002.9.9
  2. "ISRBP 2003 Poster Presentation Award", 11th Congress of ISRBP, Kosaka R, Yamane T, Sankai Y, et al., 2003.9.1
  3. "University of Tsukuba, Director Award", Kosaka R, 2004.3.25
  4. "SI2004 Best Session Award", 5th SICE, Ichihashi F, Kosaka R, Sankai Y, et al,. 2004/12/19
  5. "University of Tsukuba, President Award", Kosaka R, 2005.3.25
  6. "Barrier-Free System Instrument Foundation Award", 5th Congress of Life Support Technology, Kosaka R, Yamane T, et al., 2007.10.02
  7. "LS-BT Award", 8th Meeting of Life Science-Biotechnology, Kosaka R, Yamane T, et al., 2009.01.29
  8. "Incentive Award", 22nd Meeting of Frontier Meeting, The Society of Life Support Engineering, Yasui K, Kosaka R, et al., 2013.03.2
  9. "Poster Award", 52nd congress of JSAO. Murashige T, Kosaka R, et al., 2014.10.18
  10. "JSAO President Award", 52nd congress of JSAO. Murashige T, Kosaka R, et al., 2014.10.18
  11. "Young Researcher Award", Research Conference for Artificial Heart and Assisted Circulation of Japan. Murashige T, Kosaka R, et al., 2015.2
  12. "Helmut Reul Young Investigator Encouragement Award", 23rd Congress of ISRBP、. Murashige T, Kosaka R, et al., 2015.9.28
  13. "Poster Award", 23rd Congress of ISRBP, Murashige T, Kosaka R, et al., 2015.9.28
  14. "JSAO Young Poster Award", 53rd congress of JSAO. Saito T, Kosaka R, 2015.10
  15. "JSAO Young Poster Award", 53rd congress of JSAO. Negichi T, Kosaka R, 2015.10
  16. "JSAO Young Poster Award", 53rd congress of JSAO. Tahara Y, Kosaka R, 2015.10
  17. "Grant MERA Award", 53rd congress of JSAO. Kosaka R, 2015.10
  18. "Young Researcher Award", Research Conference for Artificial Heart and Assisted Circulation of Japan. Murashige T, Kosaka R, et al., 2016.3

4．Research projects

  1. 2003.4-2005.3 Grants-in-Aid for JSPS Fellows, Project leader, "Development of cybernetic artificial heart system"
  2. 2005.4-2008.3　JST Special Coordination Funds for the promotion of Sci. and Tech., Project member, "Establishment of evaluation method for tissue engineering"
  3. 2005.4-2006.3　Funds from Gunma prefecture, Project member, "Development of hydrodynamically levitated centrifugal blood pump"
  4. 2006.4-2007.3　Funds from Gunma prefecture, Project membe, r"Development of hydrodynamically levitated centrifugal blood pump"
  5. 2006.4-2009.3　JSPS Grant-in-Aid for Young Scientists(B)　Project leader, "Development of interactive therapeutic control between artificial heart and physiological control system"
  6. 2007.8-2010.3　NEDO Project, Project member"Development of conjugates of three-dimensional biological organ"
  7. 2009.4-2012.3　JSPS Grant-in-Aid for Young Scientists(B)　Project leader, "Development of hydrodynamically levitated centrifugal blood pump"
  8. 2009.7-2010.6　JST Astep, Project member"Establishment of in vitro hemocompatibility testing for medical device"
  9. 2009.7-2013.6　NEDO Industrial Technology Research Grant Program, Project leader, "Development of mass-flow meter using curved tube"
  10. 2009.9-2011.3　NEDO Translational Research Promotion Project, Project member, "Research and Development of the Next-generation Circulatory Assist Systems Using the Advanced Blood Pump Technologies"
  11. 2010.9-2014.3　NEDO Research and Development of Next-generation Regenerative Technology, Project member, "Evaluation of validity and reliability for implantable Ventricular Assist Device (VAD) using a small body surface area patient"
  12. 2011.4-2013.3　JSPS Grant-in-Aid for Scientific Research, Project member, "Development of portable slow continuous ultrafiltration"
  13. 2012.4-2015.3　JSPS Grant-in-Aid for Young Scientists(B)　Project leade, r"Development of long-term hydrodynamically levitated centrifugal blood pump"
  14. 2012.4-2014.3　AIST Grant (Exploratory Research), Project leader
  15. 2012.4-2013.3　Funds from Ibaraki prefecture, Project member, "Development of evaluation instrument for regenerated cartilage"
  16. 2012.11-2013.10　JST Astep, Project leader, "Development of disposable hydrodynamically levitated centrifugal blood pump"
  17. 2012.4-2015.3　Health Labor Sciences Research Grant, Project member, "Establishment of evaluation method for three dimensional regenerated cartilage"
  18. 2015.4-2017.3　JSPS Grant-in-Aid for Scientific Research (C), Project leader, "Development of a hydrodynamically levitated centrifugal blood pump by balancing the fluid force"
  19. 2015.10-2017.10　JSAO Grant, Project leader, "Development of miniaturized flow meter using a outlet cannula of a blood pump"
  20. 2018.4-2020.3　JSPS Grant-in-Aid for Scientific Research (C), Project leader, "Development of long-term hydrodynamically levitated centrifugal blood pump using AI"
  21. 2020.9-2022.3　AMED Grant for Young Researcher, Project leader
  22. 2021.4-2024.3　JSPS Grant-in-Aid for Scientific Research (B), Project leader

    Total Collaboration Projects with a company: 59