In vivo Indentation Experiment of Swine Brain
Kiyoyuki CHINZEI,  Karol, MILLER*
Biomechanics Div., Mechanical Eng. Lab., MITI/ Japan,  *Dept. Mechanical & Materials Eng., Univ. Western Australia
Key words: in vivo indentation, in vitro compression, constitutive equation, Young's modulus
Abstract
  The authors have observed compressive behavior of swine brain tissue in vitro and established a new constitutive equation. It's validation as the governing equation of the living body, in vivo, remained a question. For this purpose we designed a finite deformation experiment of in vivo swine brain by indentation.
  By introducing elastic halfspace assumption, Young's modulus is analitically derived from indentation depth, indentor diameter, and inclination of force - displacement curve. We obtained Young's modulus ranged 1.3 to 4.4 kPa. We obtained 3.8 kPa from our in vitro compression. In literature, it ranged 1.2 to 2.6 kPa from dog brain indentation[3]. As far as comparing Young's modulus, our result is in a proper range. We are preparing to simulate the experimental condition by FEM.