{"id":58,"date":"2022-11-16T00:42:11","date_gmt":"2022-11-16T00:42:11","guid":{"rendered":"http:\/\/127.0.0.1\/?page_id=58"},"modified":"2024-04-01T11:47:08","modified_gmt":"2024-04-01T02:47:08","slug":"research","status":"publish","type":"page","link":"http:\/\/127.0.0.1\/en\/research\/","title":{"rendered":"Research and Activities"},"content":{"rendered":"<p><\/p>\n<h4>Regulatory Science of Medical Devices<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-37 size-full\" src=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mdrs_700x140.jpg\" alt=\"regulatory science of medical devices\" width=\"700\" height=\"140\" srcset=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mdrs_700x140.jpg 700w, http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mdrs_700x140-300x60.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p><strong>Evaluation of medical devices<\/strong> to demonstrate the efficacy and the safety is the key to realize biomedical technology to use in society. Faster and clearer evaluation can be the competitiveness of the technology. We study the alternative methods to replace animal experiments and human subject trials, such as <em><strong>in silico<\/strong><\/em> clinical trial, <strong>organ models<\/strong> with high <strong>biofidelity<\/strong>. Topics on utilizing 3D anatomical models complying to ISO 22926 are discussed in Medical 3D Model Consortium Activities.<\/p>\n<h5>RELATED PROJECTS<\/h5>\n<ul>\n<li><a href=\"http:\/\/www.jst.go.jp\/impact\/en\/program\/15.html\" target=\"_blank\" rel=\"noopener noreferrer\">Bionic Humanoid Project<\/a>\u00a0(JST ImPACT)<\/li>\n<li><a href=\"https:\/\/med3dm.cons.aist.go.jp\" target=\"_blank\" rel=\"noopener\">Medical 3D Model Consortium<\/a> (Japanese site)<\/li>\n<li>ISO\/TC 150\/WG 14 \u201c<a href=\"https:\/\/www.iso.org\/committee\/53058.html\">Models of tissues for mechanical testing of implants<\/a>\u201c<\/li>\n<\/ul>\n<h4>Surgical Robotics<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-38\" src=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mrrobots_700x140.jpg\" alt=\"\" width=\"700\" height=\"140\" srcset=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mrrobots_700x140.jpg 700w, http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/mrrobots_700x140-300x60.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p>In 1999 we presented <strong>world\u2019s first MR compatible robot<\/strong> \u2013 robot that works while MR scanner acquires images \u2013 and we established MR compatible robotics to design, evaluate the effects between the scanner and the robot.<\/p>\n<p>Current interest is the effective use <strong>surgical robot log<\/strong> to develop machine learning for surgical training and autonomous robot control. Another topic is the <strong>ELSI (ethical, legal and social issues)<\/strong> on the use of surgical log to balance between ethical considerations and promotion of data use for\u00a0 academic and business purposes.<\/p>\n<p>Chinzei currently serves as the international project leader to develop a safety standard of surgical robots under ISO and IEC.<\/p>\n<h5>RELATED ACTIVITY<\/h5>\n<ul>\n<li>ISO\/TC 299\/JWG5 = IEC\/TC 62\/SC 62D\/JWG 35 \u201c<a href=\"http:\/\/www.iec.ch\/dyn\/www\/f?p=103:14:0::::FSP_ORG_ID,FSP_LANG_ID:12532,25\" target=\"_blank\" rel=\"noopener noreferrer\">Medical robot for surgery<\/a>\u201d Project leader<\/li>\n<li><a href=\"https:\/\/webstore.iec.ch\/publication\/29933\">IEC 80601-2-77:2019<\/a><\/li>\n<\/ul>\n<h3>Past works<\/h3>\n<h4>Biomechanics for Computer Aided Surgery<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-34\" src=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/biomech_700x140.jpg\" alt=\"\" width=\"700\" height=\"140\" srcset=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/biomech_700x140.jpg 700w, http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/biomech_700x140-300x60.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/p>\n<p>The brain, liver etc. were not the main interest of classic biomechanics, because the primal functions of these are not mechanical. However, to accurately and precisely control surgical robot or needle biopsy, one needs to predict the deformation of the organs. We started the biomechanics of such organs for surgical technology.<\/p>\n<p>We presented nonlinear constitutive models of brain tissue in the strain and strain rate that practically occur in surgery. We also presented a method to detect the instance of needle insertion using a coaxial needle. Biomechanics will be an essential science for in silico clinical trial and future of autonomous surgical robots.<\/p>\n<h4>SCC \/ Small Computing for Clinicals<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-39\" src=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/scc_700x140.jpg\" alt=\"\" width=\"700\" height=\"140\" srcset=\"http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/scc_700x140.jpg 700w, http:\/\/127.0.0.1\/wp-content\/uploads\/2022\/11\/scc_700x140-300x60.jpg 300w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/h4>\n<p>As personal computers (PC) and smartphones evolve, software works as a medical device (SaMD) is attracting market\u2019s focus, since it can disruptively reduce the cost from running on the custom designed hardware.<\/p>\n<p>Small Computing for Clinicals (SCC) is an activity to promote innovative technology and ideas into clinical research for proof of concept.<\/p>\n<h5>RELATED ACTIVITIES<\/h5>\n<ul>\n<li><a href=\"http:\/\/127.0.0.1\/old\/scc\/en\/\" target=\"_blank\" rel=\"noopener noreferrer\">Small Computing for Clinicals \/ SCC ToolKit<\/a><\/li>\n<\/ul>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Regulatory Science of Medical Devices Evaluation of medical devices to demonstrate the efficacy and the safety is the key to realize biomedical technology to use in society. Faster and clearer evaluation can be the competitiveness of the technology. We study the alternative methods to replace animal experiments and human subject trials, such as in silico &hellip; <\/p>\n<p class=\"link-more\"><a href=\"http:\/\/127.0.0.1\/en\/research\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Research and Activities&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/pages\/58"}],"collection":[{"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/comments?post=58"}],"version-history":[{"count":6,"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/pages\/58\/revisions"}],"predecessor-version":[{"id":153,"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/pages\/58\/revisions\/153"}],"wp:attachment":[{"href":"http:\/\/127.0.0.1\/en\/wp-json\/wp\/v2\/media?parent=58"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}