研究テーマ > 病理診断支援

What's the work

Pathological diagnosis for human biopsy tissues is regarded as 'gold standard' for diagnosing almost all types of cancer. However, as Fig.1 shows, since the shortage of pathologists in Japan brings pathologists huge burdens that may reasonably lead to oversight and misdiagnosis, it has become a society problem recently.

Shortage of pathologists
Fig.1. Shortage of pathologists in Japan

Aiming at reducing the pathologist's burden and improve the quality and efficiency of pathological diagnosis, our research focuses on computer-aided pathological diagnosis system utilizing pattern recognition technologies. Basically, there are two main usages(supporting modes) of a computer-aided pathological diagnosis system as Fig.2 shows below:

Screening
(a)
Double check
(b)
Fig.2. Pathological diagnosis supporting modes (a:screening, b: double check)

Top

How does it work

Detecting cancer areas from pathological images is the primary task to further help pathologists. Due to the fact that cancer cells lack of control of orderly multiplication, to find cancers, our study makes use of image precessing techniques and pattern recognition approaches to obtain various characteristics of pathological images, involving configuration of single and associated nucleus, cytoplasm, glands and background areas.(Fig.3) With these characteristics, cancer areas can be distinguished from normal areas

segmentation for glands
Fig.3. Example of segmentation of glands for further evaluation

Based on cancer detection, our interest also extands to serviceable assistance such as identification of categories of cancers and evaluation of cancer staging.

Top

Publications

Top

Want more?

Want to know more or join our study? Contact us!

Top